March 16, 1998Grinding rebar off an old cast.
Roberto SotoSubscription video-on-demand movie service Mubi has named former Fox International Channels and Liberty Global executive Roberto Soto as chief operating officer.Soto, who will report to Mubi founder and CEO Efe Cakarel, will be responsible for Mubi’s strategy and overseeing the company’s ongoing business operations globally.He was previously SVP at Fox International Channels leading commercial strategy for its pay TV channels in Latin America and then in Europe and Africa.Mubi recently secured a US$50 million (€45 million) investment from China’s Huanzi with a plan to bring Mubi’s curated film service to China later this year.Soto said: “It’s an honour and I am really excited to join the amazing Mubi team in this journey. We have a fantastic value proposition and a committed team that passionately cares about great cinema. We are excited about all the great news that we want to share with our subscribers and MUBI fans in the future.”Cakarel said: “I am delighted to welcome Roberto to the team at an incredibly exciting time for MUBI. In the next year, we will be expanding into China and continue to explore original productions. Roberto’s experience in heading strategic growth initiatives and extensive knowledge of the business come at a fantastic time.”
Reviewed by Kate Anderton, B.Sc. (Editor)Nov 14 2018Oregon State University researchers have discovered two key factors behind the intestinal inflammation that plagues people suffering from a disorder that affects their immune system.The findings, published in Clinical Immunology, are important because common variable immunodeficiency, known as CVID, afflicts hundreds of thousands of people worldwide.A significant proportion of them will have potentially life-threatening intestinal problems that include improper absorption of nutrients, particularly fat.CVID patients aren’t able to produce enough antibodies, Y-shaped proteins that mark invaders such as viruses and bacteria for destruction by the immune system. That means those people are highly susceptible to infection that often leads to chronic conditions, especially in their lungs, ears and sinuses.Related StoriesResearchers one step closer to unmasking the cause of familial MSFibrinogen a key player in health and disease, says new studyHow an orchestra of neurons control hunger pangsIn roughly 90 percent of the cases, CVID’s cause is an undetermined mix of genetic triggers; the other 10 percent have a known genetic cause.Overall, about 15 percent of CVID sufferers will end up with intestinal inflammation that will show up as weight loss associated with severe diarrhea.Researchers led by Andrey Morgun of the OSU/OHSU College of Pharmacy and Natalia Shulzhenko of Oregon State’s Carlson College of Veterinary Medicine used a novel computational approach called transkingdom network analysis to determine that a particular bacterium, Acinetobacter baumannii, is one of the main microbes responsible for CVID enteropathy.”That bacterium had not been previously found to cause intestinal illness,” said Morgun, associate professor of pharmaceutical sciences.The study, which involved 15 patients and several control subjects, also showed that CVID patients with enteropathy have dramatically lower levels of immunoglobulin A – the main antibody of the mucous membranes – in the tissue of their duodenum than do CVID patients who don’t have enteropathy. The duodenum is the first part of the small intestine, just beyond the stomach.”This finding strongly suggests that CVID patients with enteropathy exhibit more mucosal immunodeficiency than those without and are therefore more at risk for a form of gut infection that could cause intestinal inflammation,” Morgun said.Source: https://today.oregonstate.edu/news/researchers-identify-factors-behind-small-intestine-inflammation-immunodeficiency-patients
Explore further © 2018 AFP This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Rental platforms like Airbnb are hoping for a boost from a new law coming into force next month in Japan ahead of an expected surge in demand for the 2020 Olympics, but experts warn it could actually hamper business in the short-term. Currently anyone renting out a room risks falling foul of the law but short-term rentals will be legalised on June 15, clearing up a legal grey area.But the new law also introduces fresh restrictions, dismaying many who rent out rooms to tourists via Airbnb or similar platforms.Would-be renters will have to register their lodgings with the authorities and the new law limits total overnight stays to 180 days per year.The new legislation allows local authorities to impose their own restrictions too.The tourist-magnet of Kyoto, for example, has said it will only permit rentals in residential areas between mid-January and mid-March, the low season for tourist arrivals.Jake Wilczynski, Airbnb spokesman for Asia-Pacific, told AFP the new laws are a “clear sign that Japan is buying in to the idea of short-term rentals for individuals”.But many have cancelled reservations or simply taken their lodgings off the platform.”Under the new law, Airbnb hosts will not be able to accommodate guests as easily as before. I hope this doesn’t put the bar too high for us,” 41-year-old Nobuhide Kaneda, who rents out a room in Tokyo, told AFP.On an Airbnb discussion forum, an Australian host identifying herself as Narelle wrote: “I am… becoming frustrated that no one knows what is required.””I also feel the three-month timeframe to organise a notification number is unrealistic.”‘Waiting for instructions’Airbnb does not say how many properties on its platform already comply with the new laws but does not deny there have been some teething problems.Wilczynski said the firm was “in the process of discussing the issue with the Japanese Tourism Agency”.”We are waiting for instructions,” said the spokesman for Airbnb, which has informed its members of the legal changes.Despite the new restrictions, there is a huge potential market for short-term rentals as the country gears up for Tokyo 2020 and the Rugby World Cup the previous year. There will likely be strong demand for short term rentals during the 2020 Olympics in Tokyo In Denmark, Airbnb to report hosts’ rent to tax authorities Airbnb rentals have boomed in recent years, driven by an increase in tourism and a surprising lack of hotel infrastructure. With around 60,000 listings, Airbnb dominates the Japanese vacation rental market, even though it lags far behind many countries in Europe—France, for example, has 450,000 listings.And demand is poised to rise as Japan targets an influx of 40 million visitors in 2020 when it hosts the Summer Olympics—up from 29 million last year.Yasuhiro Kamiyama, CEO of Hyakusenrenma, a local firm that manages 2,000 private rentals, said the new law will begin to “normalise Japan’s Airbnb market”.He hopes to have 30,000 rental properties on his books by 2020.Mizuho, a research institute, said that “vacation rental services are unlikely to rapidly expand after (the law’s) introduction. But the potential needs are great among foreign tourists, particularly from Asia.”However, the loosening of the law will also open the door to fierce competition.E-commerce giant Rakuten is planning to launch a property rental site as soon as it comes into effect and telecom group KDDI has also set up a reservation platform.Hotel chains will also be stepping up their game, building new sites to counter “the risk of a shortage” come 2020, according to a recent research note from Mizuho. ‘Noisy neighbours’An additional problem faced by potential hosts is opposition from neighbours, who worry about noise from holidaymakers or security.According to Japanese media, there have been several cases of management companies or co-owners banning sub-lets in their buildings.Soichi Taguchi, a Japanese tourism official, said the new laws were “urgently needed to ensure public health and prevent trouble with local residents”.But Airbnb called such incidents “extremely rare”, and Hyakusenrenma’s CEO said “all the problems have stemmed from illegal rentals because neighbours did not know who was operating them”.In a bid to overcome such local difficulties, some platforms offer extra services to manage rentals, such as providing the welcome to guests, handing over keys and showing them around the property.Airbnb has forged a partnership with a service provider which registers properties with local authorities, and arranges wireless internet and cleaning after the rental. Citation: Japan’s new ‘Airbnb law’: a double-edged sword (2018, May 20) retrieved 18 July 2019 from https://phys.org/news/2018-05-japan-airbnb-law-double-edged-sword.html Nobuhide Kaneda (left) rents his apartment to Max Ikeda (back right), a Ukrainian-Japanese living in Hiroshima